How can we accelerate our capacity for innovation, lead with purpose, and enable more inclusive economic recovery and growth? In this article, we offer insights from the social impact sector and from Ashoka, an international nonprofit that has spent over four decades working with social enterprises. We share the Ashoka framework for how companies can embrace a culture of changemaking to accelerate and deepen business impact. We also showcase those within Microsoft and our partner community who are already leading the way on this journey. When a company cultivates a culture of changemaking, it experiences deep—and often unexpected—shifts, which can affect everything from hiring to core business strategy. This journey of transformation lays the groundwork for more purpose-driven leadership that can deepen our collective impact on the communities we serve across the globe.